HPV Vaccination: Predicting Its Effect on Cervical Cancer Rates

نویسندگان

  • Martial Taillefert
  • Stephanie Neuhuber
  • Gwendolyn Bristow
چکیده

Background: Early diagenetic processes involved in natural organic matter (NOM) oxidation in marine sediments have been for the most part characterized after collecting sediment cores and extracting porewaters. These techniques have proven useful for deep-sea sediments where biogeochemical processes are limited to aerobic respiration, denitrification, and manganese reduction and span over several centimeters. In coastal marine sediments, however, the concentration of NOM is so high that the spatial resolution needed to characterize these processes cannot be achieved with conventional sampling techniques. In addition, coastal sediments are influenced by tidal forcing that likely affects the processes involved in carbon oxidation. Results: In this study, we used in situ voltammetry to determine the role of tidal forcing on early diagenetic processes in intertidal salt marsh sediments. We compare ex situ measurements collected seasonally, in situ profiling measurements, and in situ time series collected at several depths in the sediment during tidal cycles at two distinct stations, a small perennial creek and a mud flat. Our results indicate that the tides coupled to the salt marsh topography drastically influence the distribution of redox geochemical species and may be responsible for local differences noted year-round in the same sediments. Monitoring wells deployed to observe the effects of the tides on the vertical component of porewater transport reveal that creek sediments, because of their confinements, are exposed to much higher hydrostatic pressure gradients than mud flats. Conclusion: Our study indicates that iron reduction can be sustained in intertidal creek sediments by a combination of physical forcing and chemical oxidation, while intertidal mud flat sediments are mainly subject to sulfate reduction. These processes likely allow microbial iron reduction to be an important terminal electron accepting process in intertidal coastal sediments. Background Salt marshes are coastal regions of high primary productivity [1,2] and receive substantial input of terrestrial organic matter [3]. Simultaneously, high rates of natural organic matter oxidation are recorded in salt marshes [4], and evidence suggests that secondary production in these environments depends more on estuarine primary production than terrestrially-derived organic matter [5]. In fact, these ecosystems are very often either balanced between autotrophy and heterotrophy [5] or carbon limPublished: 13 June 2007 Geochemical Transactions 2007, 8:6 doi:10.1186/1467-4866-8-6 Received: 21 February 2007 Accepted: 13 June 2007 This article is available from: http://www.geochemicaltransactions.com/content/8/1/6 © 2007 Taillefert et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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عنوان ژورنال:
  • PLoS Medicine

دوره 3  شماره 

صفحات  -

تاریخ انتشار 2006